B cell repertoire in infants
نویسندگان
چکیده
© 2008 Weller et al. The Rockefeller University Press $30.00 J. Exp. Med. Vol. 205 No. 6 1331-1342 www.jem.org/cgi/doi/10.1084/jem.20071555 1331 In humans, peripheral blood B cells expressing the CD27 marker and mutated Ig receptors are usually considered to be memory B cells generated in germinal centers (GCs) during immune responses to T-dependent (TD) antigens. In adults, approximately half of these CD27 + B cells are isotype-switched cells carrying surface IgG or IgA, the other half being IgM + IgD +
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